Probability of Dying from Sepsis

Sepsis, the body's extreme response to infection, kills approximately 350,000 Americans per year according to CDC data, making it a leading cause of death in US hospitals. The estimated lifetime risk of dying from sepsis is approximately 1 in 189. Sepsis occurs when the body's response to an infection damages its own tissues and organs.

Anyone can develop sepsis, but those at highest risk include adults over 65, infants under 1, people with chronic conditions (diabetes, cancer, kidney disease), immunocompromised individuals, and those with recent surgeries or hospital stays. Common infections that lead to sepsis include pneumonia, urinary tract infections, skin infections, and abdominal infections.

Early recognition and treatment are critical: for every hour treatment is delayed, mortality increases by approximately 7-8%. Warning signs include high heart rate, fever or low temperature, confusion, shortness of breath, extreme pain, and clammy skin. The acronym TIME can help: Temperature (high or low), Infection (signs of), Mental decline (confused or sleepy), and Extremely ill (worst you've felt). If you suspect sepsis, seek emergency medical care immediately and say "I am concerned about sepsis."